There are also debut call-ups for Abdul Salis Samed, Danlad Ibrahim and Kamal Sowah, while Hearts of Oak’s Daniel Afriyie Barnieh is also included.
However, some big names also missed out on the squad for the World Cup due to one reason or another.
Some couldn’t make it because they were dropped, but others also had to pull out after suffering last-minute injuries.
Charlton Athletic goalkeeper Jojo Wollacott was expected to be Ghana’s first-choice in Qatar but was ruled out due to a finger injury.
Second-choice shot-stopper Richard Ofori also suffered a knee injury at Orlando Pirates and couldn’t recover in time.
Meanwhile, Real Mallorca midfielder Baba Iddrisu could not also make the squad after suffering an injury at the weekend.
A surprise name who has been dropped, though, is Joseph Paintsil, who has been in imperious form for Genk in the Belgian topflight.
The 24-year-old winger has been involved in 14 goals this season, scoring six times and contributing eight assists.
Leicester City star Jeffrey Schlupp is also missing from the squad despite being named in the initial 55-man provisional list.
Meanwhile, Mubarak Wakaso and Cremonese teenager Felix Afena-Gyan have also failed to make Ghana’s World Cup squad.
Here are seven big-name players who missed out on Ghana’s 2022 World Cup squad: